Permanent Capital Ventures

Series A Series B

Expansion-stage VC helping founders scale go-to-market for enterprise AI and software businesses

Chicago

AI/ML · Enterprise +2

Expansion Stage · Thesis-Driven

Portal Innovations

Seed Series A

Venture development platform pairing seed capital with fully equipped lab space for university-linked life science founders.

Chicago · Providence +3

Life Sciences · BioTech +2

Venture Studio · Bio/Health-Focused

Promus Ventures

Seed Series A

Early-stage DeepTech VC investing in data-driven founders transforming mature industries including space, manufacturing, mobility, health, and energy.

Chicago · Luxembourg

DeepTech · SpaceTech +7

Global VC · Early Stage

PSP Growth

Seed Series A Series B

PSP Growth, the venture arm of Penny Pritzker's family investment firm, backs B2B software disrupting offline business processes.

Chicago

B2B Software · Unlocking the Power of Data +6

Founder-Led · Multi-Stage

S2G Investments

Series A Series B Series C

Multi-stage investor in food & agriculture, oceans, and energy. Backs late-stage venture and growth companies driving sector transition with $2.5B committed.

Chicago · San Francisco +1

ClimateTech · AgTech +7

Multi-Stage · Impact-Focused

Sandbox Industries

Seed Series A Series B

Chicago VC managing corporate-backed funds in healthcare and insurance; partners with Blue Cross Blue Shield and leading insurers as strategic LPs.

Chicago

HealthTech · InsurTech +3

Corporate VC · Multi-Stage

Sfermion

Pre-Seed Seed

Multi-strategy investment firm backing founders building the metaverse through web3, AI, and augmented and virtual reality technologies.

Chicago

AR/VR · Web3 +4

Web3-Focused · Early Stage

SNAK Venture Partners

Seed Series A

Seed-stage investor in category-defining digital marketplaces

Chicago

Category-Defining Digital Marketplaces · B2B Marketplaces +7

Category-Defining Digital Marketplaces · Seed VC

Tonic Ventures

Series A Series B

Growth-stage investor backing consumer products and brands across food, beauty, and wellness with omnichannel distribution.

Chicago

Consumer · D2C +4

Consumer-Focused · Operator-Led

u.ventures

Pre-Seed Seed Series A

Kyiv-based early-stage VC (2017), spun from Western NIS Enterprise Fund, backing Ukrainian and Moldovan founders building globally scalable startups.

Chicago · San Francisco +1

AI/ML · EdTech +5

Thesis-Driven · Early Stage

United Airlines Ventures

Seed Series A Series B

Corporate VC investing in aviation, energy, and travel innovation

Chicago

Future of Aviation · Aerospace +7

Corporate VC · Future of Aviation

Valor Equity Partners

Series A Series B Series C

Chicago growth-equity firm (2001) providing hands-on 'Scale Group' operational support to tech-enabled companies; an early Tesla and SpaceX investor.

Chicago · New York +3

Technology · Technology-Enabled +8

Operator-Led · Multi-Stage