RTW Investments

Seed Series A Series B

New York-based life sciences investment firm backing biotech and medtech across the full lifecycle from company creation through private and public stages.

New York · London +1
BioTech · MedTech +3
Multi-Stage · Global VC

RTX Ventures

Series A Series B Series C

Corporate VC investing in transformative aerospace & defense tech

Arlington
Aerospace & Defense · Aerospace +13
Corporate VC · Aerospace

Rubicon Founders

Seed Series A Series B

Nashville-based healthcare investment firm building and partnering with companies transforming care delivery and value-based models.

Nashville
HealthTech · MedTech +4
Operator-Led · Founder-Led

Rule 1 Ventures

Pre-Seed Seed Series A

Early-stage aerospace and defense VC with a parallel B2B SaaS studio. Backs pre-seed to Series A defense tech and co-founds software companies.

Atlanta
Defense Tech · Aerospace +4
Venture Studio · Defense-Focused

Run Ventures

Seed Series A

Helping founders go faster and further in their entrepreneurial journey

Salt Lake City
Artificial Intelligence Applications · AI/ML +4
Early-Stage · Emerging-Hubs

Runa Capital

Pre-Seed Seed Series A

Global VC empowering founders in early-stage deep tech and software

Luxembourg · San Francisco +3
Deeptech · Enterprise Software +3
Global VC · Software & DeepTech

Runtime Ventures

Pre-Seed Seed

Venture firm backing technical founders building data and developer infrastructure

Arlington
Enterprise Cybersecurity · Cybersecurity +4
Enterprise Cybersecurity · Technical Founders

RXR Arden Digital Ventures

Pre-Seed Seed Series A

Joint venture between real estate operators RXR and Arden Group, giving proptech and contech founders direct access to their combined platforms.

New York
Real Estate · Construction +3
Corporate VC · Multi-Stage

S Ventures (SentinelOne CVC)

Pre-Seed Seed Series A

Corporate VC investing in security data AI innovators across stages with strategic support

Mountain View
Enterprise Cybersecurity · Data +4
Corporate VC · Multi-Stage

S2G Investments

Series A Series B Series C

Multi-stage investor in food & agriculture, oceans, and energy. Backs late-stage venture and growth companies driving sector transition with $2.5B committed.

Chicago · San Francisco +1
ClimateTech · AgTech +7
Multi-Stage · Impact-Focused

S3 Ventures

Seed Series A Series B

Largest venture capital firm focused on Texas and investing nationwide

Austin
B2B Software · SaaS/Software +12
B2B Software · Healthcare

S32

Seed Series A Series B

Palo Alto-based high-conviction VC founded by GV's Bill Maris, backing obsessive founders building iconic companies across AI, biotech, cybersecurity, and enterprise.

Palo Alto
AI/ML · BioTech +6
Operator-Led · Multi-Stage

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S4S Ventures

Pre-Seed Seed Series A

Early-stage VC backed by S4 Capital/Monks and Stanhope Capital, investing in martech, adtech, data technology, and creative AI startups.

New York · London
Advertising · Marketing Tech +3
Corporate VC · Thesis-Driven

SaaS Ventures

Seed Series A

Seed-stage B2B SaaS fund backing enterprise tech founders in second- and third-tier US cities, co-investing alongside strong leads.

Bethesda · Miami
SaaS/Software · Cybersecurity +3
US-Centric · Early Stage

Sabanci Climate Ventures

Seed Series A Series B

Corporate VC arm of Sabanci Holding backing seed-to-growth energy and climate-tech startups and funds across the US and Europe.

Austin
ClimateTech · Energy +8
Corporate VC · Multi-Stage

Safar Partners

Seed Series A Series B

University-connected early-stage fund investing in MIT, Harvard, and University of Rochester spinouts across cleantech, AI/robotics, and life sciences.

Boston
ClimateTech · AI/ML +6
Early Stage · Thesis-Driven

Safer Made

Seed Series A

Venture capital firm investing in safer chemistries and materials that eliminate hazardous chemicals from consumer products and supply chains.

New Haven
ClimateTech · Materials +2
Thesis-Driven · Sector-Agnostic

Saga Ventures

Seed Series A

Operator-founded seed fund from ex-Flexport and ex-Nearside leaders plus Max Altman, backing early founders in AI, fintech, and climate tech.

Austin
Tech · AI/ML +11
Operator-Led · Founder-Led

Sageview Capital

Series B Series C

Growth equity firm providing capital and operational support to lower middle-market software and tech-enabled businesses across B2B and B2C sectors.

Palo Alto · Greenwich
SaaS/Software · Fintech +5
Growth Stage · Operator-Led

SAIC Ventures

Seed Series A Series B

Invests in dual-use and national security technology startups

Reston
Commercial Dual-Use · National Security +10
Commercial Dual-Use · National Security

Saka Ventures

Pre-Seed Seed

New York-based pre-seed and seed fund backing early-stage startups targeting large global markets across the US, India, and beyond.

New York
SaaS/Software · Enterprise +5
Solo GP · Pre-Traction

Salesforce Ventures

Seed Series A Series B

Partnering with enterprising founders from seed to IPO

San Francisco · New York +2
Enterprise Software Companies · Cloud Infrastructure +11
Enterprise Software Companies · Corporate VC

Salience Capital

Seed Series A

Early-stage venture capital firm investing in AI and enterprise software startups leveraging advanced technologies.

San Francisco
AI/ML · Enterprise +1
Early Stage · AI-Focused

Samsara BioCapital

Series A Series B Series C

Life sciences investment firm building companies around breakthrough science

Palo Alto
Bio/Health · Life Sciences +3
Bio/Health · Healthcare

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